BDBM126607 US8772283, 51

SMILES COc1ccc2OCn3c(nc(c3-c3ccccc3)-c3ccc(cc3)C3(N)CC(C)(O)C3)-c2n1

InChI Key InChIKey=NFFMKBBFNKWPHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126607   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126607(US8772283, 51)
Affinity DataIC50: 5.5nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
Go to US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126607(US8772283, 51)
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
Go to US Patent