BDBM125989 US8772297, Y250

SMILES CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)Nc2ccc(N3CCCCC3)c(c2)-c2ccco2)CC1

InChI Key InChIKey=RBPGJVUYJCINIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125989   

TargetTGF-beta receptor type-1(Human)
Kyoto University

US Patent
LigandPNGBDBM125989(US8772297, Y250)
Affinity DataIC50: 2.50E+3nMAssay Description:The biological activity of a compound was determined by measuring the activation of Smad3/Smad4 complex which is a transcription factor showing activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent