BDBM125987 US8772297, Y366

SMILES CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)Nc2ccc(cc2)N2CCN(CC2)C(=O)c2ccccc2)CC1

InChI Key InChIKey=SKJPLNMFUPLAME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125987   

TargetTGF-beta receptor type-1(Human)
Kyoto University

US Patent
LigandPNGBDBM125987(US8772297, Y366)
Affinity DataIC50: 7.30E+3nMAssay Description:The biological activity of a compound was determined by measuring the activation of Smad3/Smad4 complex which is a transcription factor showing activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent