BDBM125882 US8772305, 277

SMILES CN(C)C(=O)c1cc2cc(Nc3nccc(n3)-c3cc(ccn3)C(C)(C)C#N)ccc2[nH]1

InChI Key InChIKey=NDSGRJSFKYUANK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125882   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM125882(US8772305, 277)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent