BDBM125640 US8772305, 35

SMILES CN1CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cc(OC4CCCC4)ccn3)ccc2[nH]1

InChI Key InChIKey=HBNRGDQYJYEOTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125640   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM125640(US8772305, 35)
Affinity DataIC50: 7.90nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent