BDBM125225 US8772481, 22

SMILES Cc1cc(F)ccc1Oc1ccc2c(nncc2n1)-c1ccccc1C

InChI Key InChIKey=RCXHFYUMRAIQDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125225   

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandPNGBDBM125225(US8772481, 22)
Affinity DataIC50: 168nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent