BDBM125223 US8772481, 20

SMILES Cc1ccc(cc1-c1nncc2nc(Oc3ccc(F)cc3)ccc12)C(N)=O

InChI Key InChIKey=DZIGXCDENKQNHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125223   

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandPNGBDBM125223(US8772481, 20)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent