BDBM124430 US8759532, 83

SMILES Cn1c(Nc2ccc(Oc3ncccc3-c3cccnc3)cc2)nc2ccccc12

InChI Key InChIKey=XYAIATPPEDVOPO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124430   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

US Patent

LigandBDBM124430(US8759532, 83)Copy SMILESCopy InChI

Affinity DataIC50: 0.249nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/18/2014
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL