BDBM124347 US8759537, 178

SMILES COCCOc1cc2n(C)c(Nc3c(Cl)ccc(CNC(=O)C(C)(C)C)c3Cl)nc2cc1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=BSWQRYVQBJBXAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124347   

TargetProstaglandin E synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM124347(US8759537, 178)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 ul of recombinant human mPGES-1 (0.5 ug protein/wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent