BDBM124317 US8759537, 54

SMILES Cc1ccc(Cl)cc1NC(=O)c1cc2nc(Nc3c(Cl)ccc(CNC(=O)C(C)(C)C)c3Cl)n(C)c2cc1OCC(F)F

InChI Key InChIKey=CFBZYEYYOTVHHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124317   

TargetProstaglandin E synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM124317(US8759537, 54)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 ul of recombinant human mPGES-1 (0.5 ug protein/wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent