BDBM124221 ({2-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromoquinolin-2-yl}methyl)-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxo-3-phenylpropyl]-6-bromoquinolin-7-yl}difluoromethyl)phosphonic acid (10o)

SMILES NS(=O)C(F)(F)c1cc2nc(CC(Cc3ccc4cc(Br)c(cc4n3)C(F)(F)P(O)(O)=O)(C(=O)c3ccccc3)n3nnc4ccccc34)ccc2cc1Br

InChI Key InChIKey=UBRICIIBZMGNGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124221   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Zydus Research Centre

LigandPNGBDBM124221(({2-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromo...)
Affinity DataIC50: 4nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Zydus Research Centre

LigandPNGBDBM124221(({2-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromo...)
Affinity DataIC50: 82nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed