BDBM124122 US11547697, Compound 111::US9682141, 111

SMILES Nc1nc2cc(ccc2o1)-c1ccc2ncc(C(=O)N3CCNCC3)n2c1

InChI Key InChIKey=JRCHUTVTNGXBPZ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 124122   

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 1.00E+4nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM124122(US9682141, 111 | US11547697, Compound 111)
Affinity DataIC50: 138nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed