BDBM124083 US8754089, 4-amino-6-(((1S)-1-(3-(3-fluorophenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)ethyl)amino)-5-pyrimidinecarbonitrile

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccccn2c(=O)c1-c1cccc(F)c1

InChI Key InChIKey=QACBWDUENHPCEY-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124083   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen

US Patent

LigandBDBM124083(US8754089, 4-amino-6-(((1S)-1-(3-(3-fluorophenyl)-...)Copy SMILESCopy InChI

Affinity DataKi:  15.7nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2014
Entry Details
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