BDBM124075 US8754089, 2-((6-amino-9H-purin-9-yl)methyl)-6-methyl-3-(2-methylphenyl)-4H-pyrido[1,2-a]pyrimidin-4-one

SMILES Cc1ccccc1-c1c(Cn2cnc3c(N)ncnc23)nc2cccc(C)n2c1=O

InChI Key InChIKey=ZROSQJJHCAXSRZ-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124075   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen

US Patent

LigandBDBM124075(US8754089, 2-((6-amino-9H-purin-9-yl)methyl)-6-met...)Copy SMILESCopy InChI

Affinity DataKi:  6.28E+3nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2014
Entry Details
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