BDBM123806 2-(5-(4-Chlorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N- (4-sulfamoylphenyl)acetamide (14)

SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2nc(cc2-c2ccc(Cl)cc2)-c2ccccc2)cc1

InChI Key InChIKey=LKUITMGIUAIXSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123806   

TargetProstaglandin G/H synthase 1(Sheep)
Cairo University

LigandPNGBDBM123806(2-(5-(4-Chlorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N-...)
Affinity DataIC50: 4.77E+4nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Cairo University

LigandPNGBDBM123806(2-(5-(4-Chlorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N-...)
Affinity DataIC50: 1.17E+4nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed