BDBM123760 3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19)

SMILES Cc1[nH]nc2ncnc(N)c12

InChI Key InChIKey=VQXHGXDVBHJJJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 123760   

TargetPhospholipase D1(Human)
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))
Affinity DataIC50: 500nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))
Affinity DataIC50: 1.25E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))
Affinity DataIC50: 1.55E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed