BDBM123322 US8742106, 1.1

SMILES C[C@H](NC(=O)COc1cc(c2c(nn(C)c2n1)-c1ccccc1F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=ZNASAJGWPUTONJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123322   

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM123322(US8742106, 1.1)
Affinity DataKd:  185nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM123322(US8742106, 1.1)
Affinity DataKd:  79nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
Go to US Patent