BDBM12325 6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(propoxyimino)methyl]pyrimidin-4-amine::oxime analog 14

SMILES CCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F

InChI Key InChIKey=XPYPXGAGPAWNEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12325   

TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12325(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(...)
Affinity DataIC50: 43nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed