BDBM12281 1,1-Dimethylethyl-[2-[(1R,5S)-2(S)-[[[1-(2-amino-1,2-dioxoethyl)cyclopropyl]amino]carbonyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl]-1(S)-cyclohexyl-2-oxoethyl]carbamates::SCH 503034 Analogue 40::tert-butyl N-[(1S)-2-[(1R,2S,5S)-2-{[1-(carbamoylcarbonyl)cyclopropyl]carbamoyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl]-1-cyclohexyl-2-oxoethyl]carbamate

SMILES CC(C)(C)OC(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC1(CC1)C(=O)C(N)=O)C2(C)C

InChI Key InChIKey=IQPGHNHTPUVDJH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12281   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM12281(tert-butyl N-[(1S)-2-[(1R,2S,5S)-2-{[1-(carbamoylc...)
Affinity DataKi: >1.40E+4nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed