BDBM122453 US8729074, 11

SMILES COc1cc(cnc1OC)-c1cnc2ccc(Br)cn12

InChI Key InChIKey=JFAUJCNPBZQRCB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 122453   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

US Patent
LigandPNGBDBM122453(US8729074, 11)
Affinity DataIC50: 2.17E+3nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
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LigandPNGBDBM122453(US8729074, 11)
Affinity DataKi:  779nM IC50: 1.50E+3nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI3Kβ,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent