BDBM122447 US8729074, 2

SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cncc(c1)-c1cnc2ccccn12

InChI Key InChIKey=HUVOLDCEJFBEOC-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122447   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen

US Patent

LigandBDBM122447(US8729074, 2)Copy SMILESCopy InChI

Affinity DataKi:  1.29E+3nM IC50: 931nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI3Kβ,...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2014
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL