BDBM122401 US8729078, I-7

SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(-c4nc(cs4)C(N)=O)c3CO)c2=O)c1

InChI Key InChIKey=VDRQDEJBESIWGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122401   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM122401(US8729078, I-7)
Affinity DataIC50: 130nMpH: 7.2Assay Description:Plates assayed are 96-well polypropylene (Greiner) and 96-well 1.2 μm hydrophilic PVDF filter plates (Millipore). Concentrations reported here a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent