BDBM12145 N-({[4-(adamantan-1-yl)phenyl]carbamoyl}amino)-4-sulfamoylbenzamide::urea analog 3i

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(cc1)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12145   

TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12145(N-({[4-(adamantan-1-yl)phenyl]carbamoyl}amino)-4-s...)
Affinity DataKi:  24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12145(N-({[4-(adamantan-1-yl)phenyl]carbamoyl}amino)-4-s...)
Affinity DataKi:  33nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12145(N-({[4-(adamantan-1-yl)phenyl]carbamoyl}amino)-4-s...)
Affinity DataKi:  2.40E+3nM ΔG°:  -7.53kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed