BDBM12140 4-(N-(4-nitrophenyl)aminocarbonyl-hydrazinocarbonyl)-benzenesulfonamide::N-{[(4-nitrophenyl)carbamoyl]amino}-4-sulfamoylbenzamide::urea analog 3d

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=BBBPDAHGBPKVLX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12140   

TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12140(4-(N-(4-nitrophenyl)aminocarbonyl-hydrazinocarbony...)
Affinity DataKi:  3.20nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12140(4-(N-(4-nitrophenyl)aminocarbonyl-hydrazinocarbony...)
Affinity DataKi:  5.10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12140(4-(N-(4-nitrophenyl)aminocarbonyl-hydrazinocarbony...)
Affinity DataKi:  760nM ΔG°:  -8.20kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed