BDBM12139 4-(N-(4-ethyloxycarbonylphenyl)aminocarbonyl-hydrazinocarbonyl)-benzenesulfonamide::ethyl 4-{[N'-(4-sulfamoylphenyl)carbonylhydrazinecarbonyl]amino}benzoate::urea analog 3c

SMILES CCOC(=O)c1ccc(NC(=O)NNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=GZLBYEAKTVNBMZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12139   

TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12139(4-(N-(4-ethyloxycarbonylphenyl)aminocarbonyl-hydra...)
Affinity DataKi:  8.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12139(4-(N-(4-ethyloxycarbonylphenyl)aminocarbonyl-hydra...)
Affinity DataKi:  9nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM12139(4-(N-(4-ethyloxycarbonylphenyl)aminocarbonyl-hydra...)
Affinity DataKi:  1.20E+3nM ΔG°:  -7.94kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed