BDBM121231 US8722896, (+/-)-(3R)-2-Methyl-3-(indolin-4- ylmethylamino)-N-(9-chloro- 3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpropanamide

SMILES CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)C(C)CNCc1cccc2NCCc12

InChI Key InChIKey=CCJQUZRVYPMKLE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121231   

TargetProkineticin receptor 2(Chinese hamster)
University of California

US Patent
LigandPNGBDBM121231(US8722896, (+/-)-(3R)-2-Methyl-3-(indolin-4- ylmet...)
Affinity DataKi:  1.53nM ΔG°:  -12.5kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent

TargetProkineticin receptor 1(Chinese hamster)
University of California

US Patent
LigandPNGBDBM121231(US8722896, (+/-)-(3R)-2-Methyl-3-(indolin-4- ylmet...)
Affinity DataKi:  10.3nM ΔG°:  -11.3kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent