BDBM12105 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 13::4-tert-butyl-N-(5-phenylacetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide::4-tert-butyl-N-[5-(2-phenylacetyl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl]benzamide::CHEMBL192575

SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1[nH]nc2CN(Cc12)C(=O)Cc1ccccc1

InChI Key InChIKey=OEXOAONFGZUXSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12105   

TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12105(CHEMBL192575 | 4-tert-butyl-N-(5-phenylacetyl-1,4,...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12105(CHEMBL192575 | 4-tert-butyl-N-(5-phenylacetyl-1,4,...)
Affinity DataIC50: 130nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed