BDBM12098 3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 16::N-butyl-3-[2-(naphthalen-2-yl)acetamido]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxamide

SMILES CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccc4ccccc4c3)c2C1

InChI Key InChIKey=GRIBJJIZUIEJFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12098   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM12098(N-butyl-3-[2-(naphthalen-2-yl)acetamido]-1H,4H,5H,...)
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12098(N-butyl-3-[2-(naphthalen-2-yl)acetamido]-1H,4H,5H,...)
Affinity DataIC50: 1.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2006
Entry Details Article
PubMed