BDBM120842 2,4‐dichloro‐6‐{2‐phenyl‐5H,6H‐pyrazolo[1,5‐ c]quinazolin‐5‐yl}phenol (6g)

SMILES Oc1c(Cl)cc(Cl)cc1C1Nc2ccccc2-c2cc(nn12)-c1ccccc1

InChI Key InChIKey=SQWOBUZEINPFNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 120842   

TargetXanthine dehydrogenase/oxidase(Bovine)
Central University of Punjab

LigandPNGBDBM120842(2,4‐dichloro‐6‐{2‐phenyl&#...)
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 1.5 mL of 50 mM potassium phosphate buffer (pH 7.5), 1 mL test sample solutions (5, 10, 25, 50, and 100 µM) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
University of Nis

Curated by ChEMBL
LigandPNGBDBM120842(2,4‐dichloro‐6‐{2‐phenyl&#...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 30 mins by UV-Vis spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
University of Nis

Curated by ChEMBL
LigandPNGBDBM120842(2,4‐dichloro‐6‐{2‐phenyl&#...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed