BDBM120830 N-benzoyl-3,5-diphenylpyrazoline (2a)

SMILES O=C(N1N=C(CC1c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=BCJMDIDQGYWIAO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120830   

TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120830(N-benzoyl-3,5-diphenylpyrazoline (2a))
Affinity DataKi:  11.5nM ΔG°:  -11.3kcal/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM120830(N-benzoyl-3,5-diphenylpyrazoline (2a))
Affinity DataKi:  32nM ΔG°:  -10.6kcal/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed