BDBM120353 US8703811, 95
SMILES Cc1nc2cc(F)c(F)cc2n1-c1ccc(s1)C(=O)NC1CC1
InChI Key InChIKey=FBZQWYOZXKENJW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 120353
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Genzyme
US Patent
Genzyme
US Patent
Affinity DataIC50: 105nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair