BDBM120121 US8697715, 290::US9259470, 290

SMILES CC(C)(N)C(=O)OC[C@H](c1ccc(Cl)c(F)c1)n1ccc(cc1=O)-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=VUQWHFIOPIVZOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120121   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM120121(US8697715, 290 | US9259470, 290)
Affinity DataIC50: 15.8nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM120121(US8697715, 290 | US9259470, 290)
Affinity DataIC50: 15.8nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
Go to US Patent