BDBM120105 US8697715, 103::US9259470, 103

SMILES OC[C@H](c1cc(F)cc(F)c1)n1ccc(cc1=O)-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=YEGUKZXZMMRPDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120105   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM120105(US8697715, 103 | US9259470, 103)
Affinity DataIC50: 10.4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM120105(US8697715, 103 | US9259470, 103)
Affinity DataIC50: 10.4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
Go to US Patent