BDBM120082 US8697716, 47

SMILES FC(F)(F)C(=O)OC(=O)CN1CCC(CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1

InChI Key InChIKey=FHRYLGSBWVXRSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120082   

TargetMast/stem cell growth factor receptor Kit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM120082(US8697716, 47)
Affinity DataIC50: 100nMAssay Description:The compounds of the present invention are also specific inhibitors of c-Kit. Selection of preferred compounds of Formula I for use as c-Kit inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
Go to US Patent