BDBM119849 US8691986, 16::US9718803, 30.4

SMILES NC(=O)c1ccc(cc1F)-c1nccnc1C1CN(C1)c1ccc2ccccc2n1

InChI Key InChIKey=IXLQVIIYZMHIQJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 119849   

LigandPNGBDBM119849(US8691986, 16 | US9718803, 30.4)
Affinity DataIC50: 2.60nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent

LigandPNGBDBM119849(US8691986, 16 | US9718803, 30.4)
Affinity DataIC50: 3.30E+3nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent

LigandPNGBDBM119849(US8691986, 16 | US9718803, 30.4)
Affinity DataIC50: 2nMT: 2°CAssay Description:Enzyme Activity. An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 uL of serial diluted PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2015
Entry Details
Go to US Patent

LigandPNGBDBM119849(US8691986, 16 | US9718803, 30.4)
Affinity DataIC50: 2nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 L of serial diluted PDE10A (BPS Bioscien...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent