BDBM119819 US8691852, 37

SMILES COc1cccc(c1)-c1cc(F)c(Nc2ncccc2C(O)=O)cc1C

InChI Key InChIKey=OWIXXPFYJBLGOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119819   

LigandPNGBDBM119819(US8691852, 37)
Affinity DataIC50: 99nMpH: 8.0Assay Description:DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichlorophenol-indophenol). The substrate oxidation (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
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LigandPNGBDBM119819(US8691852, 37)
Affinity DataIC50: 99nMAssay Description:Inhibition of Homo sapiens (human) dehydroorotate dihydrogenase using 2,6-dichlorophenol-indophenol as substrate after 10 min by spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article