BDBM119775 US8691827, I-5

SMILES COC(=O)NCCNc1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1cccnc1

InChI Key InChIKey=APAVAGUBUSISEU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119775   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119775(US8691827, I-5)
Affinity DataKi:  95.3nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent