BDBM119752 US8685958, 1::US8685958, 2::US8685958, 3

SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CCC3(CCOC3)C2)cc1

InChI Key InChIKey=HLSYKQQXQCWJFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 119752   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119752(US8685958, 3 | US8685958, 2 | US8685958, 1)
Affinity DataIC50: 18nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119752(US8685958, 3 | US8685958, 2 | US8685958, 1)
Affinity DataIC50: 11nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119752(US8685958, 3 | US8685958, 2 | US8685958, 1)
Affinity DataIC50: 13nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent