BDBM119750 US8680132, C30201

SMILES CN1[C@@H](CC(C)(C)C)[C@]2([C@H]([C@@H]1C(=O)N[C@H]1C[C@@](C)(O)C1)c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=DYTUNXFWZMTYRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119750   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119750(US8680132, C30201)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent