BDBM119440 BDBM119696::US8685986, 15

SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccoc2)-c2ccc(O)cc2)cc1

InChI Key InChIKey=OUFJXJJAONPLLU-UHFFFAOYSA-N

Data  1 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 119440   

TargetHistone deacetylase 1(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 49.9nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 144nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 46.1nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 338nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 60nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 7(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 178nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 74.8nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 59nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 35nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataIC50: 72nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Ube Industries

US Patent
LigandPNGBDBM119440(US8685986, 15 | BDBM119696)
Affinity DataKi:  9.40nM ΔG°:  -11.1kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent