BDBM119369 US8673905, 86

SMILES N[C@H]1CC[C@@H](CC1)Nc1nccn2c(cnc12)-c1cccc(NCc2ccc(Cl)cc2)n1

InChI Key InChIKey=PXRKCHGZPPJPCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119369   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM119369(US8673905, 86)
Affinity DataIC50: 64nMpH: 7.5 T: 2°CAssay Description:FLT3 kinase assay was obtained from Claiper Life Sciences (Catalog #200-0423). The assay was carried out with human recombinant FLT3 (0.287 nM), fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent