BDBM118963 US11547697, Compound 15::US9682141, 15

SMILES Nc1nc2cccc(-c3ccc4nccc(-c5ccncc5)c4c3)c2o1

InChI Key InChIKey=SIPSNACXSHVDRY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 118963   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
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LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMAssay Description:The compounds described herein can be tested against recombinant mTOR (Invitrogen) in an assay containing 50 mM HEPES, pH 7.5, 1 mM EGTA, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118963(US9682141, 15 | US11547697, Compound 15)
Affinity DataIC50: 1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent