BDBM118951 US11547697, Compound 3::US9682141, 3

SMILES Nc1nc2ccc(cc2s1)-c1ccc2nccc(-c3ccncc3)c2c1

InChI Key InChIKey=MRJLLHICEJOAFF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 118951   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
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LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:The compounds described herein can be tested against recombinant mTOR (Invitrogen) in an assay containing 50 mM HEPES, pH 7.5, 1 mM EGTA, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 100nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM118951(US9682141, 3 | US11547697, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent