BDBM118104 US8664219, I-21

SMILES CC(C)(O)c1cc(Nc2n[nH]c3ncc(F)cc23)nc(n1)C1CCCCC1

InChI Key InChIKey=QOWGEVKZOPOWLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118104   

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118104(US8664219, I-21)
Affinity DataIC50: 3nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118104(US8664219, I-21)
Affinity DataIC50: 20nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent