BDBM118098 US8664219, I-10

SMILES Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(n1)C1CCCCC1

InChI Key InChIKey=GQZOLEYJVGWCGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118098   

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118098(US8664219, I-10)
Affinity DataIC50: 0.5nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118098(US8664219, I-10)
Affinity DataIC50: 6nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent