BDBM117977 US9682940, 253

SMILES NC(=O)c1ccc(cn1)C(c1ccc(Cl)cc1)c1ccc2[nH]nc(C3CCN(CC3)S(=O)(=O)C(F)(F)F)c2c1

InChI Key InChIKey=RSNGQPGDDAFSMT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 117977   

TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM117977(US9682940, 253)
Affinity DataEC50:  11nMAssay Description:CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM117977(US9682940, 253)
Affinity DataEC50:  6.93E+3nMAssay Description:CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent