BDBM116295 US8637504, 63::US9273053, 63::US9650371, 63

SMILES C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2cc3NCCn3n2)ccc1F

InChI Key InChIKey=JGSHZHANJDWJJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116295   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM116295(US8637504, 63 | US9273053, 63 | US9650371, 63)
Affinity DataIC50: 435nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM116295(US8637504, 63 | US9273053, 63 | US9650371, 63)
Affinity DataIC50: 435nMpH: 5.0Assay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM116295(US8637504, 63 | US9273053, 63 | US9650371, 63)
Affinity DataIC50: 435nMAssay Description:48.5 uL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent