BDBM116280 US8637504, 33::US9273053, 33

SMILES COCCOc1ccc(nc1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)C=CSC(N)=N1

InChI Key InChIKey=YJZQEEVMBLREDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116280   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM116280(US8637504, 33 | US9273053, 33)
Affinity DataIC50: 73nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM116280(US8637504, 33 | US9273053, 33)
Affinity DataIC50: 73nMpH: 5.0Assay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent