BDBM11568 1b-para-Cl::5-(aminomethyl)-6-(4-chlorophenyl)-2-phenylpyrimidin-4-amine::Aminomethylpyrimidine 1bf

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=XJUZSPSKYMVGEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11568   

TargetDipeptidyl peptidase 4(Human)
Hoffmann-La Roche

LigandPNGBDBM11568(5-(aminomethyl)-6-(4-chlorophenyl)-2-phenylpyrimid...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Hoffmann-La Roche

LigandPNGBDBM11568(5-(aminomethyl)-6-(4-chlorophenyl)-2-phenylpyrimid...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed