BDBM115194 4‐(4,5‐dihydro‐1,3‐thiazol‐2‐ylsulfanyl)‐N‐(3,4‐ dimethoxyphenyl)‐6‐[(3,4‐dimethoxyphenyl)methyl]‐ 1,3,5‐triazin‐2‐amine::UT-A1 inhibitor C1

SMILES COc1ccc(Cc2nc(Nc3ccc(OC)c(OC)c3)nc(SC3=NCCS3)n2)cc1OC

InChI Key InChIKey=UWKDKMYSAXPHGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 115194   

TargetUrea transporter 2(Rat)
University of California San Francisco

LigandPNGBDBM115194(4‐(4,5‐dihydro‐1,3‐thiazol...)
Affinity DataIC50: 4.20E+3nMAssay Description:The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details Article
PubMed
TargetUrea transporter 1(Rat)
University of California San Francisco

LigandPNGBDBM115194(4‐(4,5‐dihydro‐1,3‐thiazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Erythrocyte suspension (100 µL) was added to each well of a 96-well microplate to which test compounds were added. After 15 min incubation, 20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details Article
PubMed